Correlation of mRNA delivery timing and protein expression in lipid-based transfection
نویسندگان
چکیده
منابع مشابه
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چکیده ندارد.
15 صفحه اولQuality criteria for finding genes with high mRNA-protein expression correlation and coexpression correlation.
mRNA expression is widely used as a proxy for protein expression. However, their true relation is not known and two genes with the same mRNA levels might have different abundances of respective proteins. A related question is whether the coexpression of mRNA for gene pairs is reflected by the corresponding protein pairs. We examined the mRNA-protein correlation for both expression and coexpress...
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BACKGROUND Fully differentiated adipocytes are considered to be refractory to introduction of siRNA via lipid-based transfection. However, large scale siRNA-based loss-of-function screening of adipocytes using either electroporation or virally-mediated transfection approaches can be prohibitively complex and expensive. METHODOLOGY/PRINCIPAL FINDINGS We present a method for introducing small i...
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ژورنال
عنوان ژورنال: Integrative Biology
سال: 2019
ISSN: 1757-9708
DOI: 10.1093/intbio/zyz030